cGMP Description

Guanosine 3’5’-cyclic Monophosphate, aswell accepted as cGMP, is an important intracellular additional agent that has been apparent to collaborate with the extracellular signals nitric oxide and natriuretic peptides, as able-bodied as arbitrate their action. cGMP interacts with the receptors cGMP-dependent protein kinases, cGMP-regulated channels, and cGMP-regulated circadian nucleotide phosphodiesterases. The admixture can actuate protein kinase G, and it has been apparent that animated levels of cGMP in vivo stimulates cGMP-dependent protein kinase (PKG). Research shows that cGMP can abolish apoptosis in rat ovarian follicles, and that it is metabolized bound in the attendance of agnate phosphodiesterases.