Bis(tri-n-butyltin)oxide (TBTO) is one of the organotin compounds that have been used as biocides and occur as persistent environmental pollutants. Human exposure to these compounds occurs through consumption of meat and fish products in which they accumulate. The most sensitive endpoint of TBTO exposure is immunotoxicity. TBTO causes thymus atrophy and thereby interferes with T-lymphocyte-mediated immune responses. Tributyltin compounds have been found to adversely affect a wide range of cellular components and processes in many species, organ systems, and cell types.
For each chemical with a positive (carcinogenic) experiment in the Carcinogenic Potency Database (CPDB), results are included on carcinogenic potency (TD50) in each species and target sites in males and females. Positivity is determined by an author’s opinion in a published paper. If all experimental results in the CDPB are negative in a sex-species group, “no positive” appears. The Carcinogenic Potency Database (CPDB) is a unique and widely used international resource of the results of 6540 chronic, long-term animal cancer tests on 1547 chemicals. Bis tri-n-butyltin oxide is a liquid derived by the hydrolysis of tributyl tin chloride, used as an agent to control the growth of most fungi, bacteria and marine organisms in plastics.
CAS: 56-35-9
Molecular Formula: 24H54OSn2
Molecular Weight: 596.1g/mol
MSDS Name: Bis(tri-n-butyltin) oxide stabilized 96% (stabilized with 0.1%
Synonym: HBD; Hexabutylditin oxide
Bis tri-n-butyltin oxide is a clear colorless liquid with its melting point -45°C and boiling point 180 °C2 mm Hg(lit.). It is water insoluble,air and moiture sensitive. It can be used as a bactericide, fungicide and chemical intermediate. This product should be stored at 4°C .
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