Where to get Fmoc-Tyr(tBu)-OH?

Fmoc-Tyr(tBu)-OH
CAS No.:71989-38-3
Molecular formula:C28H29NO5
Molecular weight:459.55
Description
Purity (HPLC):98.5% min
Appearance:White powder
Melting point:146~148℃
Specific rotation(20/D): -27o (c=1, DMF)
Fmoc-amino acid Wang resins are prepared using special proprietary procedures that minimize racemization. For more information about pre-loaded Wang resins and other resins for peptide synthesis, please call us at 888.692.9111 or click here.
t-Boc amino acid derivatives had been used dominantly for the SPPS until the Fmoc chemistry was introduced to overcome the t-Boc chemistry problems, repetitive TFA treatment which might catalyze the side reactions and cleave the peptide chain prematurely. In Fmoc synthesis, the growing peptide is subjected to mild base treatment using piperidine to remove the Fmoc group, and TFA is required only for the final deprotection and cleavage from the resin. The comparison experiments between Fmoc and t-Boc approache indicate that Fmoc chemistry is more reliable and tends to give the desired peptides in better purities.
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